The Initiative for Electrified and Autonomous Mobility (IEAM) is a US Economic Development Administration university center based in the Purdue School of Engineering Technology at IU Indianapolis. In partnership with the Transportation and Autonomous Systems Institute (TASI) and the Center for Excellence in Manufacturing (CEM), IEAM will focus on electrified and autonomous transportation. The imminent and ongoing global disruption of technologies in transportation, provide a substantial opportunity for the US and the Indiana region to lead and capture economic benefits from this disruption. The Indiana region needs to prepare for this change and how it will affect logistics, manufacturing and transportation industries.